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Product name
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Lemairamin
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Other name
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2-Propenamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)-;
Lemairamin (WGX-50)
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CAS No.
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29946-61-0
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Molecular formula
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C19H21NO3
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Molecular weight
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311.37
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Purity
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98.0%
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Appearance
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White to off-white powder
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Application
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Dietary Supplement Raw Material
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1.Product introduction
Lemairamin or Wgx50 is a natural compound extracted from chili peppers that has shown promising results in preventing Alzheimer's disease. Studies have found that it can inhibit Aβ-induced neuronal apoptosis, reduce neuronal calcium toxicity, and reduce the accumulation of Aβ oligomers in the cerebral cortex. Additionally, wgx50 has been shown to improve cognitive performance in mice. Research suggests that wgx50 has the potential to prevent protein-protein assembly between amyloid molecules. Overall, wgx50 has the potential to prevent Alzheimer's disease and may provide new avenues for the development of drugs targeting Aβ oligomers. Additionally, WGX-50 exhibits significant anti-inflammatory activity, which makes it a promising candidate for the treatment of inflammatory diseases. WGX-50 has been found to have significant effects on the skin, such as reducing wrinkles and improving skin elasticity. In addition to the natural compounds extracted from the plant Zanthoxylum bungeanum, there are currently more synthetic compounds that are used in various applications and are more suitable for the market.
2.Features
(1) High purity: Lemairamin can obtain high-purity products through refining production processes. High purity means better bioavailability and fewer adverse reactions.
(2) Safety: High safety, few adverse reactions.
(3) Stability: Lemairamin has good stability and can maintain its activity and effect under different environments and storage conditions.
(4) Easy to absorb: Lemairamin can be quickly absorbed by the human body and distributed to different tissues and organs.
3.Application
Lemairamin is an amide compound extracted from the bark of the Zanthoxylum bungeanum plant. Currently used as a dietary supplement, it also acts as an agonist of the alpha7 nicotinic acetylcholine receptor (α7nAChR), which reduces neuroinflammation in Alzheimer's disease, and is completely synthetic.Wgx50 has shown encouraging results in preclinical studies, including inhibiting Aβ-induced neuronal apoptosis, reducing neuronal calcium toxicity, reducing the accumulation of Aβ oligomers in the cerebral cortex, and improving cognitive performance in mice.
